منابع مشابه
ARF sees Pdgfrβ through the miR
Comment on: Iqbal N, et al. Cell Cycle 2014; 13:792–800; PMID:24401748; http://dx.doi.org/10.4161/cc.27725 Sara M Reed, Frederick W Quelle, and Dawn E Quelle*; Department of Pharmacology; The University of Iowa; Carver College of Medicine; Iowa City, IA USA; Medical Scientist Training Program; The University of Iowa; Carver College of Medicine; Iowa City, IA USA; Holden Comprehensive Cancer Cen...
متن کاملTyrosine Kinase Inhibitors Regulate OPG through Inhibition of PDGFRβ
Nilotinib and imatinib are tyrosine kinase inhibitors (TKIs) used in the treatment of chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST). In vitro, imatinib and nilotinib inhibit osteoclastogenesis, and in patients they reduce levels of bone resorption. One of the mechanisms that might underlie these effects is an increase in the production of osteoprotegerin (OPG). In th...
متن کاملDark Matter Sees The Light
We construct a Dark Matter (DM) annihilation module that can encompass the predictions from a wide array of models built to explain the recently reported PAMELA and ATIC/PPB-BETS excesses. We present a detailed analysis of the injection spectrums for DM annihilation and quantitatively demonstrate effects that have previously not been included from the particle physics perspective. With this mod...
متن کاملGuanylyl cyclase sees the light
Cyclic guanosine monophosphate (cGMP) is a critical second messenger that regulates cardiovascular function and vision in humans. Two recent papers, including one in BMC Structural Biology, have revealed atomic structures of the enzymes that catalyze the synthesis of cGMP providing new clues about the molecular basis of substrate specificity and allosteric regulation in nucleotide cyclases.
متن کاملThe hand that ‘sees’ to grasp
New findings advance our understanding of how vision is used to guide the hand during object grasping.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Cycle
سال: 2014
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.28900